Key result
Abnormal peri-organ or intra-organ fat deposition and metabolic syndrome are associated with chronic obstructive pulmonary disease, though further research is needed to define clinical implications.
Why the study?
Systemic inflammation in COPD predisposes to metabolic disorders and abnormal peri-organ or intra-organ fat deposition, which negatively affect outcomes and cardiovascular risk.
Abnormal peri-organ or intra-organ fat deposition and metabolic syndrome are important comorbidities in COPD that may negatively affect cardiovascular risk and outcomes.
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May link COPD inflammation to metabolic comorbidities worsening outcomes; leaves open metabolite-targeted trials.
Katsiki et al. (2020) conducted a review in Chronic Obstructive Pulmonary Disease (COPD). Metabolic syndrome and abnormal peri-organ or intra-organ fat (APIFat) deposition was evaluated. Abnormal peri-organ or intra-organ fat deposition and metabolic syndrome are associated with chronic obstructive pulmonary disease, though further research is needed to define clinical implications.
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