Key result
Planimetry of the aortic valve area using 64-slice CT correlated well with transthoracic echocardiography (r=0.88, p<0.001) and transesophageal echocardiography (r=0.99, p<0.0001).
Why the study?
Does 64-slice CT planimetry accurately measure aortic valve area compared to TTE and TEE in patients with aortic stenosis?
Observational (n=36)
Does 64-slice CT planimetry accurately measure aortic valve area compared to TTE and TEE in patients with aortic stenosis?
Effect estimate: r = 0.88 (TTE), r = 0.99 (TEE)
p-value: p=<0.001 (TTE), <0.0001 (TEE)
64-slice CT provides accurate planimetry of the aortic valve area in patients with aortic stenosis, correlating well with standard echocardiographic measurements.
May support CT planimetry when echocardiography is limited; leaves open prospective outcome validation.
OBJECTIVE: The purpose of our study was to evaluate planimetry of the aortic valve area with 64-slice CT in comparison with transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) in patients with aortic stenosis. MATERIALS AND METHODS: Thirty-six patients with aortic valve disease referred for coronary 64-slice CT angiography were examined. Planimetry of the aortic valve area with 64-slice CT was compared with TTE using the Doppler continuity equation for calculation of the aortic valve area and with planimetric measurement of the aortic valve area using TEE. RESULTS: Planimetry of the aortic valve area with CT (1.11 +/- 0.42 cm2) showed a good correlation with TTE (1.05 +/- 0.42 cm2) (r = 0.88, p < 0.001) in 32 patients and a good correlation with TEE (1.41 +/- 1.61 cm2) (r = 0.99, p < 0.0001) in 10 patients. The mean and maximum transvalvular pressure gradients were correlated with the aortic valve area as measured with CT (r = -0.68, p = 0.0001; and r = -0.67, p = 0.0001, respectively). Beta-blockers were not given (mean heart rate, 62.5 +/- 10.7 beats per minute). CONCLUSION: MDCT allows accurate planimetry of the aortic valve area in patients with aortic stenosis. In patients referred for 64-slice CT coronary angiography, concomitant aortic stenosis can be identified and evaluated.
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Feuchtner et al. (2007) conducted an observational in Aortic stenosis (n=36). 64-slice CT planimetry vs. Transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) was evaluated on Correlation of aortic valve area measurement (r = 0.88 (TTE), r = 0.99 (TEE), p=<0.001 (TTE), <0.0001 (TEE)). Planimetry of the aortic valve area using 64-slice CT correlated well with transthoracic echocardiography (r=0.88, p<0.001) and transesophageal echocardiography (r=0.99, p<0.0001).
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