ADVERTISEMENT RETURN TO ISSUEEditorialNEXTTop Down ProteomicsJohn R. Yates, III† and Neil L. Kelleher‡View Author Information† Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, United States‡ Departments of Chemistry and Molecular Biosciences, the Proteomics Center of Excellence, and the Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois 60208, United StatesCite this: Anal. Chem. 2013, 85, 13, 6151Publication Date (Web):May 24, 2013Publication History Published online24 May 2013Published inissue 2 July 2013https://pubs.acs.org/doi/10.1021/ac401484rhttps://doi.org/10.1021/ac401484reditorialACS PublicationsCopyright © 2013 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views3199Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (120 KB) Get e-AlertscloseSUBJECTS:Ions,Mass spectrometry,Modification,Protein identification,Proteomics Get e-Alerts
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Yates et al. (2013) studied this question.