Key result
In 23 randomized controlled trials investigating hemidiaphragmatic paralysis after brachial plexus blocks, the median Fragility Index was 4, indicating that statistically significant results in this field tend to be fragile.
Why the study?
The study was conducted to characterize the fragility index of statistically significant results reported in randomized controlled trials investigating the incidence of hemidiaphragmatic paralysis after brachial plexus blocks.
Population
23 RCTs investigating hemidiaphragmatic paralysis after brachial plexus blocks
Design
Systematic review
Authors
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Fragile HDP findings in brachial plexus block RCTs warrant cautious interpretation; challenges reliance on current evidence and supports larger trials.
Systematic Review (n=23)
Effect estimate: median FI 4
Statistically significant results in RCTs investigating hemidiaphragmatic paralysis after brachial plexus blocks are often fragile, suggesting that findings frequently depend on a small number of events.
Luo et al. (2023) conducted a systematic review in Hemidiaphragmatic paralysis after brachial plexus blocks (n=23). Brachial plexus blocks vs. Other nerve blocks and injection techniques was evaluated on Fragility index (FI) (median FI 4). In 23 randomized controlled trials investigating hemidiaphragmatic paralysis after brachial plexus blocks, the median Fragility Index was 4, indicating that statistically significant results in this field tend to be fragile.
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