The division surgeon procured fifty ampules of amyl nitrite, containing 3 minims each.These were used in all doubtful cases.Of course the influence on the heart, as far as it concerns our experiment, is very similar to the effect of exercise.However, there is one great advantage : It is possible to listen to the heart during its period of increasing activity and acceleration, and there is no attending dyspnea as a disturbing factor.In other words, as the patient administers the drug to himself the observer listens
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McGuire et al. (1919) studied this question.
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