Key result
Overweight men demonstrated significantly lower cerebral oxygenation 20 minutes post-exercise compared to normal-weight men (1.0 vs 13.9 μmol/L; p=0.024).
Why the study?
Obesity negatively impacts cardiovascular function and may increase cerebrovascular complications during exercise.
Does overweight status alter hemodynamic and cerebral oxygenation responses during and after high-intensity exercise in men?
Cross-Sectional (n=32)
Does overweight status alter hemodynamic and cerebral oxygenation responses during and after high-intensity exercise in men?
Absolute Event Rate: 1% vs 13.9%
p-value: p=0.024
Overweight men exhibit impaired cerebral oxygenation and higher vascular resistance following high-intensity exercise, suggesting a need for caution when prescribing vigorous exercise in this population.
Hypothesis-generating for altered post-exercise responses in overweight men; prospective trials needed before changing exercise recommendations.
Obesity has negative impacts on cardiovascular function and may increase cerebrovascular complications during exercise. We compared hemodynamic and cerebral oxygen changes during high-intensity exercise between overweight (OW) and normal-weight (NW) individuals. Eighteen NW and fourteen OW male individuals performed high-intensity (70% of peak oxygen uptake, VO2peak) cycling exercises for 30 min. Hemodynamics were measured using a bioelectrical impedance device, and cerebral oxygenation status was measured using a near-infrared spectrophotometer during and after exercise. The VO2peak of NW individuals was significantly higher than that of OW individuals (41.3 ± 5.7 vs. 30.0 ± 5.0 mL/min/kg, respectively; p < 0.05). During the 30 min exercise, both groups exhibited an increase in oxygenated hemoglobin (O2Hb) (p < 0.001), deoxygenated hemoglobin (p < 0.001), and cardiac output with increasing time. Post-exercise, cardiac output and systemic vascular resistance were significantly higher in the OW group than in the NW group (p < 0.05). The O2Hb in the NW group was significantly higher at post-exercise times of 20 min (13.9 ± 7.0 μmol/L) and 30 min (12.3 ± 8.7 μmol/L) than that in the OW group (1.0 ± 13.1 μmol/L and 0.6 ± 10.0 μmol/L, respectively; p = 0.024 vs. 0.023, respectively). OW participants demonstrated lower cerebral oxygenation and higher vascular resistance in the post-exercise phase than non-OW subjects. These physiological responses should be considered while engaging OW and obese individuals in vigorous exercise.
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Wang et al. (2023) conducted a cross-sectional in Overweight (n=32). Overweight vs. Normal-weight was evaluated on Oxygenated hemoglobin (O2Hb) at 20 min post-exercise (p=0.024). Overweight men demonstrated significantly lower cerebral oxygenation 20 minutes post-exercise compared to normal-weight men (1.0 vs 13.9 μmol/L; p=0.024).
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