nsulin-like growth factor-1 (IGF-1) plays a role in the regulation of myocardial structure and function. IGF-1 is capable of improving cardiac muscle survival, growth, calcium signaling, and differentiation. 1 Among various actions of IGF-1 on heart, the ability of IGF-1 to counteract apoptosis of cardiomyocytes has drawn significant attention in recent years. 3]
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Ping H. Wang (2001) studied this question.
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