Nitridomanganese(V) Complexes:  Design, Preparation, and Use as Nitrogen Atom-Transfer Reagents

Oxidation of organic substrates by direct oxygen-atom from transition-metal complexes is of fundamental and has been subject to intensive investigation. selective methods for alkene epoxidation dihydroxylation have been described and are commonly in synthesis. By contrast, significantly fewer reagents and protocols are available for the analogous -atom-transfer process, despite the enormous utility of such methodology. Recent efforts by other groups to develop general olefin amination have led to impressive advances in both metalcatalyzed hydroxyamination and aziridination. Our in this area has resulted in the preparation and of novel nitridomanganese complexes may be activated for nitrogen-atom transfer. Pivotal the success of this research has been the development new protocols for the construction of these nitride (Mn≡N) reagents. These systems have to be versatile and effective aminating agents with classes of olefins which include both silyl enol and glycals (eq 1). The following account documents findings and highlights the unique chemistry these complexes as nitrogen-atom-transfer reagents.