Key result
Renal denervation may not decrease ambulatory blood pressure in isolated systolic hypertension compared to sham, and its risks like renal artery stenosis likely outweigh the benefits.
Why the study?
Does renal denervation reduce ambulatory blood pressure in patients with isolated systolic hypertension?
Does renal denervation reduce ambulatory blood pressure in patients with isolated systolic hypertension?
Answers are grounded in this paper and cite their sources.
This commentary cautions against using renal denervation for isolated systolic hypertension due to the lack of controlled evidence and potential risks like renal artery stenosis, recommending adjusted drug treatment instead.
Ewen et al. recently reported in the journal Hypertension that they investigated, for the first time, the effect of renal denerva tion on blood pressure in 63 patients with isolated systolic hypertension (Ewen et al., 2014). The authors concluded that renal denervation reduced office and ambula- tory blood pressure in patients with iso- lated systolic hypertension (Ewen et al., 2014). However, this conclusion may not be drawn, as renal denervation may not decrease ambulatory blood pressure in these patients. The potential risk of renal denervation may overweigh its benefit in patients with isolated systolic hypertension. Therefore, adjusted drug treatment may be recommended to these patients before renal denervation.
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Yutang Wang (2014) conducted an editorial in Isolated systolic hypertension (n=63). Renal denervation vs. Sham procedure / Adjusted drug treatment was evaluated on 24-h ambulatory systolic blood pressure. Renal denervation may not decrease ambulatory blood pressure in isolated systolic hypertension compared to sham, and its risks like renal artery stenosis likely outweigh the benefits.
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