Key result
Newly diagnosed hypertensive patients had significantly higher mean total cholesterol (211.2 vs 161.3 mg/dl, p<0.05) and a 78% prevalence of elevated total cholesterol compared to normotensive controls.
Why the study?
Variations from normal lipid profiles frequently coincide with hypertension, motivating an evaluation of lipid profile abnormalities in hypertensive patients.
Are lipid profile abnormalities more prevalent in newly diagnosed hypertensive patients compared to normotensive controls?
Observational (n=200)
No
Are lipid profile abnormalities more prevalent in newly diagnosed hypertensive patients compared to normotensive controls?
Newly diagnosed hypertensive patients have a significantly higher prevalence of dyslipidemia compared to normotensive controls, highlighting the need for early lipid screening and management in this population.
Lipid abnormalities in hypertension support screening; leaves open whether intervention alters outcomes in prospective studies.
Objective and Aim: Variations from the norm of lipid profile and hypertension frequently coincide. The present study was conducted to evaluate the lipid profile abnormalities among hypertensive patients. Material and Method: This is a retrospective observational study conducted at a primary diabetes and cardiology clinic OPD among 200 patients whose clinical records are well maintained or fully available at the clinics registry. After getting individual patient consent the data collected and analysed to draw a study conclusion. Result: 48.4 ± 6.9 years was the mean average age of study group whereas for the control group it was 49.3± 5.9 years. In the age group 40-49 years occurrence of hypertension was seen in extreme as compare to other age group. In study groups total cholesterol, triglyceride, HDL Cholesterol and LDL Cholesterol were significantly higher as compared to control group (p<0.05). Among the hypertensive subjects most frequently occurring abnormality was elevated TC (78%), followed by elevated LDL (66%). Conclusion: Among newly diagnosed hypertensives lipid variations are highly prevalent as documented in this study. Hypertension is the one of the major risk factor for coronary artery disease and for this biologic interrelations between serum lipids and blood pressure further worsen the condition. Hence to prevent complications early detection and aggressive treatment of dyslipidemia in hypertensive patients should be carried out.
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Kumar et al. (2021) conducted an observational in Newly diagnosed hypertension (n=200). Newly diagnosed hypertension vs. Normotensive controls was evaluated on Mean Total Cholesterol (mg/dl) (p=<0.05). Newly diagnosed hypertensive patients had significantly higher mean total cholesterol (211.2 vs 161.3 mg/dl, p<0.05) and a 78% prevalence of elevated total cholesterol compared to normotensive controls.
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