Threonine 144 in cardiac troponin I is a key residue modulating cardiac myofilament length-dependent activation, the cellular basis of the Frank-Starling law.
No takes yet. Share an insight, caveat, or question.
Identifies Thr144 as modulator of myofilament length dependence in vitro; leaves open translation to in vivo Frank-Starling mechanics or therapy.
Tachampa et al. (2007) studied this question.