What question did this study set out to answer?

To determine whether fine screen blood filtration can prevent post-traumatic pulmonary insufficiency in trauma patients undergoing massive blood transfusion.

April 1, 1973Archives of Surgery

Prevention of Post-Traumatic Pulmonary Insufficiency

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Authors

GRGeorge J. ReulHouston Methodist

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Implication

Prospective study demonstrates reduced pulmonary insufficiency with fine screen filters in massive transfusion trauma patients, indicating filtration protects lung function.

Key Points

To determine whether fine screen blood filtration can prevent post-traumatic pulmonary insufficiency in trauma patients undergoing massive blood transfusion.
Conducted a prospective study in 29 trauma patients requiring massive blood transfusions, with an overall average of 19 units transfused.
Assigned 13 patients to receive 10 to 63 units of blood through a 40-μ uniform pore size fine screen filter (Ultipor) and 16 control patients to receive 10 to 40 units through a standard 170-μ filter.
Evaluated pulmonary outcomes and correlated clinical signs of lung insufficiency with histologic findings from lung biopsy specimens.
Pulmonary insufficiency developed in 2 of 13 patients (15.4%) in the fine screen filter group compared with 8 of 16 patients (50.0%) in the standard filter control group.
Histopathologic findings from lung biopsy specimens correlated directly with the observed reduction in pulmonary insufficiency in the fine screen filter group.

Cite This Study

George J. Reul (1973) studied this question.

synapsesocial.com/papers/6a77d039d3a6aa87c6bdf7c2 https://doi.org/10.1001/archsurg.1973.01350160008002

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Implication

Prospective study demonstrates reduced pulmonary insufficiency with fine screen filters in massive transfusion trauma patients, indicating filtration protects lung function.

Prevention of Post-Traumatic Pulmonary Insufficiency

Discussion

Member takes

Implication

Key Points

Cite This Study

Prevention of Post-Traumatic Pulmonary Insufficiency

Discussion

Member takes

Implication

Key Points

Cite This Study

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