Highlights the importance of recognizing and managing potentially fatal serotonin syndrome caused by interactions between SSRIs and peri-operative drugs in cardiac surgery patients.
Alerts clinicians to rare SSRI interactions in cardiac surgery; hypothesis-generating and leaves open systematic incidence studies.
Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat depression. We report a case of serotonin syndrome following cardiac surgery. This syndrome is rare in the cardiac literature. The clinical features, diagnosis and management of this unusual syndrome are described. In patients with polypharmacy, it is important to take cognisance of serotonergic antidepressants and anticipate their potential interactions with drugs used peri-operatively. Early recognition and treatment is important as this condition is potentially fatal.
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SHANMUGAM et al. (2008) studied this question.
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