The clinical, virological, and biochemical course of 3 chronic HBsAg carriers who developed acute hepatitis A is described. Two of the patients had pre-existent chronic active hepatitis. The clinical course in each case was benign with resolution within one month, and there was a marked fall in HBsAg titre in one of the patients with chronic active hepatitis.
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Viola et al. (1982) studied this question.
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