The modulating effects of green rooibos (Aspalathuslinearis) extract on vascular function and antioxidantstatus in obese Wistar rats

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This research aims to explore the cardioprotective effects of green rooibos extract on cardiovascular disease risk factors in obese Wistar rats.
Obese Wistar rats (N=20 per group) were subjected to a high-fat diet for 16 weeks and treated with green rooibos extract for 6 weeks.
Blood pressure, vascular reactivity, and oxidative stress markers were measured.
Western blots were performed to assess specific cell-signaling proteins in aortic tissues.
High-fat diet led to increased blood pressure and impaired vasodilation.
GRT treatment significantly improved PKB and AMPK expression and antioxidant enzyme activity.
GRT reduced levels of malondialdehyde, indicating decreased oxidative stress.

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Investigates green rooibos extract improving cardiovascular risk factors in obese rats, suggesting potential therapeutic benefits.

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Obasa et al. (2021) studied this question.

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