February 27, 2016Journal of Pediatric Rehabilitation MedicineOpen Access

Age at onset of first signs or symptoms predicts age at loss of ambulation in Duchenne and Becker Muscular Dystrophy: Data from the MD STARnet

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Why the study?

Does the age at onset of first signs and symptoms predict the age at loss of ambulation in males with childhood-onset Duchenne and Becker Muscular Dystrophies?

Population

Male cases with childhood-onset Duchenne and Becker Muscular Dystrophies from the population-based Muscular…

Design

Cohort

Authors

ECEmma CiafaloniUniversity of Rochester Medical Center AKAnil KumarUniversity of Fort Hare KLKe LiuChina Pharmaceutical University

Discussion

Member takes

Implication

Earlier symptom onset may flag faster LOA progression in DBMD; leaves open added prognostic value beyond genetics or steroids.

Structured PICO

Does the age at onset of first signs and symptoms predict the age at loss of ambulation in males with childhood-onset Duchenne and Becker Muscular Dystrophies?

Population

Male cases with childhood-onset Duchenne and Becker Muscular Dystrophies (DBMD) from the population-based Muscular Dystrophy Surveillance, Tracking, and Research Network (MD STARnet)

Intervention

Age at onset of first signs and symptoms (SS)

Outcome

Onset age at loss of ambulation (LOA)hard clinical

Earlier onset of first signs and symptoms in Duchenne and Becker muscular dystrophies predicts an earlier age at loss of ambulation.

Cite This Study

Ciafaloni et al. (2016) studied this question.

synapsesocial.com/papers/6a77f833d2fa2470761f391a https://doi.org/10.3233/prm-160361

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Age at onset of first signs or symptoms predicts age at loss of ambulation in Duchenne and Becker Muscular Dystrophy: Data from the MD STARnet

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Age at onset of first signs or symptoms predicts age at loss of ambulation in Duchenne and Becker Muscular Dystrophy: Data from the MD STARnet

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider