Why the study?
Chronic smoking adversely affects vascular and hormonal systems and promotes atherosclerosis, thrombogenesis, and vascular occlusion, which adversely affects nephropathy prognosis.
Does smoking affect the levels of hSCRP and microalbumin compared to non-smokers?
Does smoking affect the levels of hSCRP and microalbumin compared to non-smokers?
May signal heightened CV and renal risks in smokers; hypothesis-generating, should not yet change practice.
Background: Smoking is associated increase in morbidity and mortality from various diseases. Increasing evidence suggests that chronic smoking adversely affects vascular and hormonal systems. Smoking plays a significant role in the development of atherosclerosis, thrombogenesis and vascular occlusion, which further adversely affects the prognosis of nephropathies. Aim and. Objectives: to estimate and compare the levels of hSCRP and microalbumin levels in smokers and non-smokers. Materials and Methods: Under aseptic precautions random venous blood sample of 2 mL was drawn from ante-cubital vein and collected in red top tube and serum was separated and analysed for high sensitivity C reactive protein (hSCRP). Early morning mid-stream urine was used for urine microalbumin estimation and the same sample was used for urine microscopy to exclude patients with urinary tract infection. Statistical Analysis: All statistical tests was performed using SPSS software. For comparisons of different variables student’s t-test and Chi-square test were be used. Pearson coefficient of correlation was used for assessment of relationship between variables. A p value <0.05 was considered statistically significant.
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Turankar et al. (2022) studied this question.
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