August 9, 2026Current Opinion in Allergy and Clinical Immunology
Safety of allergen immunotherapy: real-world evidence
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Overview
Review summarizes real-world safety data on allergen immunotherapy, indicating its general tolerability and risk factors.
Key Points
- This review aims to evaluate the safety of allergen immunotherapy through real-world evidence, focusing on adverse events and risk factors.
- Summarizes recent real-world evidence from registries and cohort studies on allergen immunotherapy safety.
- Evaluates the frequency and severity of adverse events across diverse healthcare settings and practices.
- Highlights evidence from recent findings in venom allergy and risk stratification methods.
- Allergen immunotherapy is generally well tolerated, with infrequent systemic reactions and no reported fatal reactions from sublingual immunotherapy.
- Despite the overall safety, rare systemic reactions do occur, emphasizing the need for careful monitoring during subcutaneous immunotherapy.
- New findings refine risk stratification, helping identify high-risk patients for more optimal treatment approaches.
Cite This Study
Asllani et al. (2026) studied this question.