S ummary Spironolactone has been found to have anti‐androgenic properties and to be useful in the treatment of female hirsulism. Benefits have also been noted in the treatment of mature age onset or persistent acne in females. The mechanism of action of this drug is mainly via a peripheral anti‐androgenic effect but it may also result in decreased androgen production. The results of a number of clinical studies are discussed with particular reference to the side effects of spironolactone. Guidelines for treatment of hirsutism and female mature age acne are given.
No takes yet. Share an insight, caveat, or question.
Annette Callan (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: