Pain: the size and measure of the problem Basic mechanisms of pain and pain relief Factors affecting the severity of pain Consequences of postoperative pain The pharmacology of opioid analgesics The pharmacology of non-opioid analgesics The pharmacology of drugs with secondary analgesic properties The pharmacology of local anaesthetics Choices in the management of postoperative pain Regional anaesthesia and analgesia Spinally applied opioids Pain relief for problem patients Pharmacokinetic considerations What next?.
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A 1989 study studied this question.