From time to time it is of value to review important investigations and relevant studies to see how coherent they are in relation to an accepted hypothesis, to find where they disagree and to devise new experimental approaches for the solution of the problem. The author of this monograph is well qualified to examine such an important subject in this manner. The book, however, is more than a review of the movement of fluid and electrolytes and the nature of restraints the vital membranes of the body impose on them. It is a judicious and scholarly attempt to construct a background for a more rational analysis of the functional pathology of various clinical and pathologic disturbances. The disturbances related to renal injury receive major consideration. The author develops his thesis from fundamental discussions of chemical forces that control exchanges of fluid and solutes, the nature and movements of interstitial fluid
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A 1936 study studied this question.