Key result
Mitral annular fractional area change was identified as an independent predictor of reduced left ventricular apical rotation (≤6 degrees) in healthy adults (P < 0.003).
Why the study?
Several factors may influence LV rotational mechanics under normal circumstances, but the relationship between LV rotational mechanics and mitral annular size and function in healthy subjects remains to be clarified.
Cross-Sectional (n=118)
Yes
In healthy subjects, left ventricular apical rotation correlates with end-systolic mitral annular size and function, suggesting a physiological coupling between these structures.
LV apical rotation associates with MA function in healthy adults; leaves open relevance in disease or outcomes.
INTRODUCTION: Left ventricular (LV) twist is considered an essential part of LV function due to oppositely directed LV basal and apical rotations. Several factors could play a role in determining LV rotational mechanics in normal circumstances. This study aimed to investigate the relationship between LV rotational mechanics and mitral annular (MA) size and function in healthy subjects. METHODS: The study comprised 118 healthy adult volunteers (mean age: 31.5 ± 11.8 years, 50 males). All subjects had undergone complete two-dimensional (2D) Doppler echocardiography and three-dimensional speckle-tracking echocardiography (3DSTE) at the same time by the same echocardiography equipment. RESULTS: The normal mean LV apical and basal rotations proved to be 9.57 ± 3.33 and -3.75 ± 1.98°, respectively. LV apical rotation correlated with end-systolic MA diameter, area, perimeter, fractional area change, and fractional shortening, but did not correlate with any end-diastolic mitral annular morphologic parameters. The logistic regression model identified MA fractional area change as an independent predictor of ≤6° left ventricular apical rotation (P < 0.003). CONCLUSIONS: Correlations could be detected between apical LV rotation and end-systolic MA size and function, suggesting relationships between MA dimensions and function and LV rotational mechanics.
No takes yet. Share an insight, caveat, or question.
Nemes et al. (2020) conducted a cross-sectional in Healthy subjects (n=118). Mitral annular size and function was evaluated on Predictors of reduced (≤6°) left ventricular apical rotation (p=<0.003). Mitral annular fractional area change was identified as an independent predictor of reduced left ventricular apical rotation (≤6 degrees) in healthy adults (P < 0.003).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: