Key result
Neutrophil lymphocyte ratio was significantly higher in acute coronary syndrome patients requiring percutaneous coronary intervention, demonstrating moderate diagnostic value (AUC 0.691) for predicting PCI.
Why the study?
The study aimed to determine the roles of neutrophil count, MPV, and NLR in diagnosing ACS and differentiating between STEMI and NSTEMI subtypes among emergency department patients with chest pain.
Does Neutrophil Lymphocyte Ratio (NLR) predict the diagnosis of ACS and the need for percutaneous coronary intervention in patients presenting to the emergency department with chest pain?
Cross-Sectional (n=402)
No
Does Neutrophil Lymphocyte Ratio (NLR) predict the diagnosis of ACS and the need for percutaneous coronary intervention in patients presenting to the emergency department with chest pain?
NLR is an inexpensive and easily accessible biomarker that can assist in diagnosing acute coronary syndrome and determining the need for percutaneous coronary intervention, particularly in male patients.
May aid emergency ACS evaluation; hypothesis-generating and requires prospective validation before adoption.
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Savrun et al. (2021) conducted a cross-sectional in Acute Coronary Syndrome (n=402). Neutrophil Lymphocyte Ratio (NLR) vs. Patients not requiring Percutaneous Coronary Intervention (PCI) was evaluated on Prediction of the need for Percutaneous Coronary Intervention (PCI) (AUC 0.691, 95% CI 0.634-0.747, p=<0.001). Neutrophil lymphocyte ratio was significantly higher in acute coronary syndrome patients requiring percutaneous coronary intervention, demonstrating moderate diagnostic value (AUC 0.691) for predicting PCI.
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