Key result
Transcatheter left atrial appendage closure was associated with new, clinically unapparent cerebral embolic lesions in 32% of patients, with most showing no gliotic transformation at 45 days.
Cohort (n=28)
No
Transcatheter left atrial appendage closure frequently causes new, clinically silent cerebral embolic lesions on MRI, though most do not result in permanent gliotic transformation or neurological deficits.
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Silent cerebral lesions occur in ~32% of LAA closures; leaves open whether they warrant embolic protection or alter long-term outcomes.
Majunke et al. (2017) conducted a cohort in Patients undergoing transcatheter left atrial appendage closure (n=28). Transcatheter left atrial appendage closure was evaluated on Silent and clinically apparent cerebral embolic events. Transcatheter left atrial appendage closure was associated with new, clinically unapparent cerebral embolic lesions in 32% of patients, with most showing no gliotic transformation at 45 days.
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