Key result
Inadequate treatment of venous thromboembolism leads to significant morbidity, mortality, and costs, which may be mitigated by newer oral anticoagulants offering simpler management.
Why the study?
Do oral anticoagulants in development reduce the economic burden and improve clinical outcomes compared to traditional anticoagulants in patients at risk for VTE?
Do oral anticoagulants in development reduce the economic burden and improve clinical outcomes compared to traditional anticoagulants in patients at risk for VTE?
Answers are grounded in this paper and cite their sources.
Newer oral anticoagulants may reduce the significant economic and clinical burden of VTE by improving treatment adherence and simplifying management.
Venous thromboembolism (VTE) is a common and serious medical complication among medical and surgical patients, both in the hospital and postdischarge. Patients with venous stasis or vascular damage or those with underlying hypercoagulable disorders, including cancer, are at risk of developing VTE. The clinical consequences of inadequate treatment of VTE can result in significant patient morbidity and mortality. The direct health care costs and indirect societal costs related to VTE and its complications are high. Traditional anticoagulants can reduce recurrent VTE but they present costly management challenges. Oral anticoagulants currently in development offer simpler management compared with the established agents, potentially resulting in improved adherence with VTE treatment regimens and better outcomes. Reductions in recurrent VTE and its associated complications could translate into reduced direct and indirect costs.
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Paul P. Dobesh (2013) conducted a review in Venous thromboembolism. Oral anticoagulants vs. Traditional anticoagulants was evaluated. Inadequate treatment of venous thromboembolism leads to significant morbidity, mortality, and costs, which may be mitigated by newer oral anticoagulants offering simpler management.
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