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May 9, 2022Frontiers in NeurologyOpen Access

Favorable mRS at discharge (<3) was significantly higher in urban areas (63.03%) compared to semi-urban (48.75%) and rural areas (31.35%) (global p=0.0000), with higher lethality in rural (13.56%) vs urban patients (10.64%).

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Why the study?

Information is scarce in Latin America regarding factors related to stroke patient outcomes in rural versus urban areas.

Comparison

Rural vs semi-urban vs urban origin

Design

Prospective cohort study

Follow-up

3 months

Authors

NLNatalia Llanos‐LeytonCPCarlos A. PardoGPGabriel David Pinilla-Monsalve

Discussion

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Member takes

Overview

Rural stroke patients had worse functional outcomes; leaves open whether regional networks can reduce disparities in Latin America.

Structured PICO

P
Population
555 acute stroke patients (432 with ischemic stroke) over 18 years old admitted to a high complexity hospital in southwestern Colombia within a stroke code context, including 357 from urban, 80 from semi-urban, and 118 from rural areas.
O
Outcome
Change in modified Rankin scale (mRS) between onset and discharge/3-months follow-uphard clinical

Acute stroke patients from rural areas experience worse functional outcomes and higher mortality at discharge and 3 months compared to urban patients, highlighting significant pre-hospital and healthcare access disparities.

Limitations

  • Small sample size compared to international studies
  • Potential bias from prospective data collection after institutional code-stroke creation
  • Loss to follow-up due to telephone changes
  • Single-center study
  • Lack of data in rural hospitals about stroke cases
  • Potential underdiagnosis and information biases for dyslipidemia in rural patients

Cite This Study

Llanos‐Leyton et al. (2022) studied this question.

synapsesocial.com/papers/6a7951608d250a4360f37a51https://doi.org/10.3389/fneur.2022.869772
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