This case report of craniorachischisis emphasizes the critical need for early prenatal care, first-trimester ultrasound screening, and adequate preconception folic acid supplementation in high-risk patients.
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Supports vaginal delivery feasibility after prostaglandin induction in craniorachischisis; leaves open optimal prevention strategies pending larger studies.
Craniorachischisis is an extreme example of anencephaly and spina bifida. It is an example for defective neural groove closure. A female dead fetus delivered by caesarian section in Malla Reddy Medical College, Hyderabad found to have features of craniorachischisis. There was complete absence of calvaria and brain; the entire vertebral column was open on the posterior side with spinal nerves seen outside. On dissection, all thoracic and abdominal organs were found to be normal. Since infant organs are in high demand for pediatric transplantation, laws must be framed to use the normal organs from these cases of neural tube defects.
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N. Rao (2015) studied this question.
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