This case highlights a rare association between pseudomyxoma peritonei and pericardial involvement, emphasizing the importance of early echocardiographic evaluation in these patients presenting with chest pain to prevent cardiac tamponade.
May support colchicine for pericardial effusion in pseudomyxoma peritonei; hypothesis-generating and should not yet change practice.
Pseudomyxoma peritonei (PMP) is an uncommon clinical entity characterised by the progressive accumulation of mucinous ascites within the peritoneal cavity. We describe the case of a 59-year-old man with recurrent PMP secondary to an appendiceal mucinous neoplasm, who presented with acute chest pain and dyspnoea. Investigations revealed transient constrictive pericarditis with mild pericardial effusion and associated precardiac lymphadenopathy. Management with anti-inflammatory therapy led to clinical and echocardiographic resolution of pericardial inflammation. This case highlights an association between PMP and pericardial involvement, emphasising the importance of early echocardiographic evaluation in PMP patients presenting with chest pain. Recognising this rare association may guide timely and appropriate management, preventing the development of potentially life-threatening cardiac tamponade.
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Brogiolo et al. (2025) studied this question.
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