The authors used a gantry tilt of 20 degrees in five patients to allow fine-needle aspiration biopsy of peripheral pulmonary lesions that were difficult to approach with a vertical alignment because of overlying ribs. This method allowed a direct approach to the lesion in all five cases, with the entire needle path visible in the scanning plane, avoidance of vital structures, and traversal of a minimal amount of normal lung parenchyma.
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Stern et al. (1993) studied this question.