Key points are not available for this paper at this time.
Answers are grounded in this paper and cite their sources.
Ectopic wave origins remain incompletely characterized; leaves open mechanistic targets for arrhythmia prevention research.
The well-organized contraction of each heartbeat is enabled by an electrical wave traversing and exciting the myocardium in a regular manner. Perturbations to this wave, referred to as arrhythmias, can lead to lethal fibrillation if not treated within minutes. One manner in which arrhythmias originate is an ill-fated interaction of the regular electrical signal controlling the heartbeat, the sinus wave, with an ectopic stimulus. It is not fully understood how and when ectopic waves are generated. Based on mathematical models, we show that ectopic beats can be characterized in terms of unstable eigenmodes of the resting state.
No takes yet. Share an insight, caveat, or question.
Tveito et al. (2011) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: