THE average physician confronted with the subject of porphyrin metabolism pictures either a bewilderingly complex group of strange pigments obtained from stools and urine or an exceedingly rare disease characterized by sensitivity to light and acute abdominal pain. Actually, porphyrin derivatives are an essential part of the respiratory enzymes present in all living cells, and an understanding of their nature and relations may be expected to lead to improvement in the diagnosis and treatment of many human diseases. It is the purpose of this paper to discuss one of these porphyrins, protoporphyrin, and to indicate the role it plays in . . .
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Merrill L. Welcker (1945) studied this question.
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