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February 9, 2023PLoS ONEOpen Access

Directed acyclic graphs in perioperative observational research–A systematic review and critique against best practice recommendations

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Why the study?

Recent best-practice guidance for constructing DAGs has been published in the ESC-DAG protocol, but adherence to these principles within perioperative literature had not been assessed.

Design

Systematic review

Authors

MWMatthew WatsonUniversity of CambridgeSHSebastian HickmanUniversity of CambridgeKDKaya Dreesbeimdiek

Discussion

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Implication

DAGs reduce bias risk in observational analyses; extends transparent causal modeling standards for cardiovascular research.

Structured PICO

P
Population
19 perioperative observational studies incorporating a Directed Acyclic Graph (DAG)
O
Outcome
Adherence to the 'Evidence synthesis for constructing DAGs' (ESC-DAG) protocol principles

DAGs constructed for use in perioperative observational literature do not consistently adhere to best practice recommendations, highlighting a need for increased methodological transparency.

Cite This Study

Watson et al. (2023) studied this question.

synapsesocial.com/papers/6a7975bd4c448619ca0dbe1dhttps://doi.org/10.1371/journal.pone.0281259
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Also Consider

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  1. 1Causal inference with observational data: the need for triangulation of evidence2021 · 236 citations
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