Urea space was measured in cattle by infusing (iv) a known quantity of urea (approximately 130 mg/kg body wt) and withdrawing blood samples at varying times after infusion for plasma urea analysis. The relation between urea space determined at 12 or 15 min after urea infusion in 12 steers was highly correlated with percentage empty body fat and percentage empty body water.
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Preston et al. (1973) studied this question.