How can the pathological examination of a mucosectomy specimen be improved?

The risk of lymph node metastasis has to be smaller than the risk of a surgical procedure to perform local endoscopic resection of curative intention. Depending on the site within the gastrointestinal tract low and high risk groups can be identified. Criteria differ somewhat with the location. For histological work up enbloc resections are the most preferable specimen since the status of resection could be demonstrated histologically. The method of endoscopic resection for early neoplasms is widespread in the colon but is limited to centres in the oesophagus and partially in the stomach. Because of possible complications it is good to have a surgeon close by and for diagnostic purposes a close communication with your pathologist.