Post psychotic depression: The Fulbourn cohort

A comparison is reported, based on a 10 year follow-up, between an index sample of 29 subjects suffering from schizophrenia and post psychotic depression and a control sample of 41 subjects suffering from schizophrenia alone, all having had their first admission to the same hospital in 1974. The index subjects were significantly older on onset of schizophrenia and exhibited more auditory hallucinations. Follow-up patients with post psychotic depression were admitted more often, but their admissions were shorter. No difference was found between the two groups in the frequency of family history of affective disorder, in the duration of treatment with depot neuroleptics or in the dose level of the depot injection received immediately prior to readmission.