Neuropsychiatric Approaches for Human Suicide Prediction and Management

Human suicide accounts for 2% Human mortality worldwide. Some widely accepted medical knowledge suggests that suicide events or episodes are strongly associated with neuropsychiatric events and changes. We previously accumulate data and evidence that neuropsychiatric study and interference may help us to reduce suicide rates and mortality. Given the useful evidence and therapy in the clinic, cutting off unnecessary suicide-induced genes or molecules will ultimately reduce suicide-induced mortality in statistically significant manner. This article discusses how the genetic, epigenetic and molecular phenotypes can be manipulated in the lab animals and a framework of neuropsychiatric changes and interferences in patients. Possible drug targets and treatments are also discussed.