Why the study?
Does the hypertriglyceridemic waist phenotype associate with increased markers of systemic inflammation and endothelial dysfunction in women?
Population
507 Iranian women aged 40-60 years
Comparison
Hypertriglyceridemic waist phenotype vs Normal waist circumference and normal serum…
Design
Cross-sectional
Key result
The hypertriglyceridemic waist phenotype in women was associated with significantly higher C-reactive protein (2.7 vs 1.3 mg/l; p=0.003) and other inflammatory markers compared to normal controls.
Authors
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May flag higher inflammatory risk in women with this phenotype; hypothesis-generating for prospective cardiometabolic outcome studies.
Cross-Sectional (n=507)
Does the hypertriglyceridemic waist phenotype associate with increased markers of systemic inflammation and endothelial dysfunction in women?
Absolute Event Rate: 2.7% vs 1.3%
p-value: p=0.003
The hypertriglyceridemic waist phenotype is positively associated with elevated markers of systemic inflammation and endothelial dysfunction in women, independent of body mass index.
Esmaillzadeh et al. (2010) conducted a cross-sectional in Hypertriglyceridemic waist phenotype (n=507). Hypertriglyceridemic waist (HW) phenotype vs. Normal waist circumference and normal serum TG levels was evaluated on C-reactive protein (mg/l) (p=0.003). The hypertriglyceridemic waist phenotype in women was associated with significantly higher C-reactive protein (2.7 vs 1.3 mg/l; p=0.003) and other inflammatory markers compared to normal controls.