Key result
A six-minute walk distance of 300 meters or less post-cardiac rehabilitation was associated with a 4.5-fold higher prevalence of major adverse cardiac events compared to walking over 300 meters (45.5% vs 10.5%, p=0.029).
Why the study?
Studies have reported the role of the 6MWD test in predicting outcomes for CHD patients, but none had performed the investigation in the Aceh setting.
Does achieving a 6-minute walk distance >300 meters reduce MACE in atherosclerotic CHD patients post-cardiac rehabilitation?
Cross-Sectional (n=30)
No
Does achieving a 6-minute walk distance >300 meters reduce MACE in atherosclerotic CHD patients post-cardiac rehabilitation?
Relative Risk: 4.5
Absolute Event Rate: 45.5% vs 10.5%
p-value: p=0.029
Achieving a six-minute walk distance of more than 300 meters post-cardiac rehabilitation is associated with a significantly lower risk of major adverse cardiac events in patients with atherosclerotic coronary heart disease.
Plaque accumulation in the coronary arteries is a major cause of coronary heart disease (CHD), a disease infamously known as a contributor for global death burden. Major adverse cardiac events (MACE) pose significant risks for CHD patients, highlighting the urgency of effective management and cardiac rehabilitation in CHD management. Studies have reported the role of the six-minute walk distance (6MWD) test in predicting outcomes for CHD patients; however, none have performed the investigation in Aceh setting. The aim of this study was to investigate the reliability of 6MWD as a prognostic factor for post-cardiac rehabilitation of patients with atherosclerotic CHD. A cross-sectional study was conducted in Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia. MACE was determined through in-person interviews, and phone calls with 30 atherosclerotic CHD patients who completed cardiac rehabilitation between August 2018 and September 2020. The association between 6MWD and prognosis, assessed by MACE incidence, was calculated. The results revealed that 6MWD was strongly associated with MACE occurrence during post-cardiac rehabilitation (p=0.029; prevalence ratio 4.5). Furthermore, CHD patients achieving 6MWD of more than 300 meters exhibited a lower incidence of MACE (10.5%) than patients with 6MWD of less than 300 meters (45.5%). In conclusion, the present study sheds light on the importance of improving functional capacity in patients with atherosclerotic CHD post-cardiac rehabilitation due to its significant association with the prognosis.
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Ridwan et al. (2023) conducted a cross-sectional in Atherosclerotic coronary heart disease (n=30). Six-minute walk distance (6MWD) ≤300 meters vs. 6MWD >300 meters was evaluated on Major adverse cardiac event (MACE) (PR 4.5, p=0.029). A six-minute walk distance of 300 meters or less post-cardiac rehabilitation was associated with a 4.5-fold higher prevalence of major adverse cardiac events compared to walking over 300 meters (45.5% vs 10.5%, p=0.029).
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