Key result
A 10-month multicomponent exercise intervention significantly increased cortical thickness in the middle temporal (p<0.001) and temporal pole (p<0.001) compared with a health education control.
Why the study?
The study was conducted to examine cortical thickness changes associated with a multicomponent exercise intervention combining physical exercise and cognitive training in older adults with cognitive decline.
Does a multicomponent exercise intervention combining physical exercise and cognitive training improve cortical thickness in older adults with cognitive decline?
Population
280 older adults with cognitive decline
Comparison
Multicomponent exercise and cognitive training vs health education control
Design
Secondary analysis of neuroimaging data from a randomized controlled trial
Follow-up
10 months
Authors
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Supports multicomponent exercise for brain structural health; extends RCT evidence on physical activity benefits.
RCT (n=280)
randomly assigned
Does a multicomponent exercise intervention combining physical exercise and cognitive training improve cortical thickness in older adults with cognitive decline?
p-value: p=<0.001
A 10-month multicomponent exercise program combining physical and cognitive training significantly increases cortical thickness in temporal regions in older adults with cognitive decline.
Bae et al. (2020) conducted an RCT in cognitive decline (n=280). Multicomponent exercise combining physical exercise and cognitive training vs. Health education was evaluated on Cortical thickness changes (p=<0.001). A 10-month multicomponent exercise intervention significantly increased cortical thickness in the middle temporal (p<0.001) and temporal pole (p<0.001) compared with a health education control.
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