Answers are grounded in this paper and cite their sources.
This study revealed a novel anti-inflammatory mechanism of FGF21 via inhibiting the hepatocyte-TLR4-IL-17A signaling in NASH-HCC models. The negative feedback loop on the hepatocyte-TLR4-IL-17A axis could be a potential anti-carcinogenetic mechanism for FGF21 to prevent NASH-HCC transition.
No takes yet. Share an insight, caveat, or question.
Zheng et al. (2020) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: