Population
Rat kangaroo cells (PtK2) and WI-38 human fibroblasts
Comparison
10% dimethyl sulfoxide (Me2SO) vs Normal medium or cells before/after Me2SO…
Design
Preclinical
Authors
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DMSO may confound actin studies in vitro; leaves open relevance to in vivo cardiovascular models.
Dimethyl sulfoxide reversibly induces the translocation of cytoplasmic actin into the nucleus where it forms filamentous bundles in cultured cells.
Sanger et al. (1980) studied this question.
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