Animal study reveals optogenetic control of eye pressure in cilia-deficient mice, indicating phosphoinositide signaling is essential for aqueous humor balance.
mice that lack functional cilia. Thus, our study is the first to use optogenetics to regulate eye pressure and demonstrate that tight regulation of phosphoinositides is critical for aqueous humor homeostasis in both normal and diseased eyes.
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Prosseda et al. (2020) studied this question.
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