Key result
Poststroke epilepsy in young adults is linked to ~80% higher long-term mortality.
Cohort (n=631)
Answers are grounded in this paper and cite their sources.
BACKGROUND AND PURPOSE: Poststroke epilepsy is a common complication after a young stroke. We investigated the association between poststroke epilepsy and mortality. METHODS: We performed a prospective cohort study among 631 patients with a first-ever transient ischemic attack or ischemic stroke, aged 18 to 50 years. Survival analysis and Cox proportional hazard analysis were used to estimate cumulative mortality and hazard ratios for patients with and without epilepsy. RESULTS: After mean follow-up of 12.5 years (SD 8.6), 76 (12.0%) developed poststroke epilepsy. Case fatality was 27.4% for patients with poststroke epilepsy and 2.1% for those without. Poststroke epilepsy was associated with 30-day mortality (hazard ratio, 4.8; 95% confidence interval, 1.7-14.0) and long-term mortality (hazard ratio, 1.8; 95% confidence interval, 1.2-2.9). CONCLUSIONS: Epilepsy is a common problem after a young stroke and is associated with an increased short-term and long-term mortality.
No takes yet. Share an insight, caveat, or question.
Arntz et al. (2015) conducted a cohort in First-ever transient ischemic attack or ischemic stroke at a young age (n=631). Poststroke epilepsy vs. No poststroke epilepsy was evaluated on Long-term mortality (HR 1.8, 95% CI 1.2-2.9). Poststroke epilepsy in young stroke patients was associated with increased 30-day mortality (HR 4.8; 95% CI 1.7-14.0) and long-term mortality (HR 1.8; 95% CI 1.2-2.9).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: