Key result
Endurance athletes exhibit longer intrinsic sinus cycle and AV node refractory periods under autonomic blockade.
Why the study?
Endurance athletes have a higher prevalence of sinus bradycardia and AV conduction abnormalities, and nonautonomic factors may be responsible for their longer AV node refractory period.
Does endurance training induce intrinsic electrophysiologic adaptations in the sinus and AV nodes independent of autonomic influences in healthy males?
Comparison
Athletes vs untrained individuals before and after autonomic pharmacologic blockade
Design
Invasive electrophysiologic comparative study
Authors
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Endurance athletes exhibit intrinsic electrophysiologic adaptations in the sinus and AV nodes that are independent of autonomic influences, explaining their higher prevalence of bradycardia and conduction abnormalities.
Observational (n=12)
Does endurance training induce intrinsic electrophysiologic adaptations in the sinus and AV nodes independent of autonomic influences in healthy males?
Endurance athletes exhibit intrinsic electrophysiologic adaptations in the sinus and AV nodes that are independent of autonomic influences, explaining their higher prevalence of bradycardia and conduction abnormalities.
Stein et al. (2002) conducted an observational in Healthy (n=12). Endurance athletic training vs. Untrained individuals was evaluated on Sinus cycle length (SCL) and AV node electrophysiologic parameters under autonomic blockade. Endurance athletes demonstrated longer sinus cycle lengths and AV node refractory periods compared to untrained individuals under double-autonomic blockade, indicating intrinsic physiologic adaptations.
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