Transformational change in the Anthropocene epoch

As humanity enters the Anthropocene epoch, fundamental disruptions to our way of living, including serious effects on human health, have become increasingly likely due to severe global environmental changes. Several planetary boundaries have already been transgressed (eg, rate of biodiversity loss, and changes to the global nitrogen cycle).1 Stabilising Earth in a habitable state requires transformational changes—ie, changing systemic structures causing the problems,2 at multiple levels (eg, local, national, and global) and in virtually all sectors of society (eg, decarbonisation of economies, and improved governance).