Symptoms and Signs Referable to the Basal Ganglia in Brain Tumor

CEREBRAL tumor is not generally considered a cause of extrapyramidal signs and symptoms, and it has been stated by Kinnier Wilson¹and others²that neoplastic involvement of the basal ganglia is often asymptomatic. Focal neurologic signs are not usually observed until the internal capsule is involved. The relevant literature consists largely of individual case reports. It is the purpose of this paper to describe a series of 12 cases of intracranial tumor and manifestations indicating involvement of the extrapyramidal system and to review the pertinent literature. In 1923 Parker³described the case of a 12-year-old boy with a clinical picture of Parkinsonism who was found to have a tumor involving both thalami. Moersch⁴in 1928 reported the case of a man aged 28 with Parkinsonian facies and gait and a tremor of the left upper extremity who recovered completely after the removal of a right parasagittal