Key result
Amiodarone prophylaxis decreases the incidence of atrial fibrillation after coronary artery bypass graft surgery, whereas its use as a treatment does not significantly reduce hospital length of stay.
Why the study?
Does amiodarone prevent or treat atrial fibrillation in patients post coronary artery bypass graft?
Does amiodarone prevent or treat atrial fibrillation in patients post coronary artery bypass graft?
Amiodarone is primarily supported as a prophylactic measure to decrease the incidence of postoperative atrial fibrillation in CABG patients, with limited evidence for its use as a treatment.
May support amiodarone prophylaxis to prevent post-CABG AF; leaves open treatment effects on length of stay.
BACKGROUND: Atrial fibrilation (AF) is the most common complication following heart surgeries; it often occurs in patients after coronary artery bypass graft (CABG). The purpose of this review is to categorize prophylaxes or treatment by administration of Amiodaron in patients with CABG. DATA RESOURCES: We searched google scholar, pubmed, and Cochrane Library databases (the period 1970-2010) for articles on Amiodaron in CABG and cardiac surgery. A total of 1 561 articles were identified, and 30 articles met the criteria and were enrolled in this review. RESULTS: Most studies supported Amiodarone for prophylaxi purpose in patients who were performed with CABG; few papers supported Amiodaron as a drug for treating CABG. The prophylaxis can decrease the incidence rate of AF in CABG, but if it uses as a treatment, the side effect of Amiodaron will decrease because all of the patients will not get Amiodarone. In the other hand use of Amiodarone as a treatment does not influence the length of hospital stay significantly but these kinds of study are so few. CONCLUSION: No appropriate therapeutic method has been defined for AF. At present, the common way of treating AF following cardiac surgery is mainly based on prophylaxis in medical books and references.
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Habibollahi et al. (2016) conducted a review in Atrial fibrillation post coronary artery bypass graft (CABG). Amiodarone was evaluated on Incidence of atrial fibrillation and length of hospital stay. Amiodarone prophylaxis decreases the incidence of atrial fibrillation after coronary artery bypass graft surgery, whereas its use as a treatment does not significantly reduce hospital length of stay.
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