Key result
Partial VTE prophylaxis significantly increased the risk of hospital-acquired VTE (OR 3.09) and in-hospital death (OR 1.48) compared with appropriate ACCP-recommended prophylaxis in hospitalized cancer patients.
Why the study?
Does appropriate VTE prophylaxis reduce VTE events, mortality, and hospital costs in hospitalized cancer patients compared to partial prophylaxis?
Cohort (n=83,794)
Yes
Does appropriate VTE prophylaxis reduce VTE events, mortality, and hospital costs in hospitalized cancer patients compared to partial prophylaxis?
Answers are grounded in this paper and cite their sources.
Appropriate adherence to ACCP guidelines for VTE prophylaxis in hospitalized cancer patients significantly reduces hospital-acquired VTE, mortality, and costs compared to partial prophylaxis.
Prophylaxis is often underused and inappropriately prescribed. This study compares the efficacy and cost of appropriate and partial prophylaxis in cancer patients at risk for VTE.
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Amin et al. (2009) conducted a cohort in Cancer patients at risk of venous thromboembolism (VTE) (n=83,794). Partial VTE prophylaxis vs. Appropriate VTE prophylaxis was evaluated on Hospital-acquired VTE events (OR 3.09, 95% CI 2.51 to 3.80, p=<0.001). Partial VTE prophylaxis significantly increased the risk of hospital-acquired VTE (OR 3.09) and in-hospital death (OR 1.48) compared with appropriate ACCP-recommended prophylaxis in hospitalized cancer patients.
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