Key result
Maximal exercise revealed a muscle-specific spectral profile of muscle activation that is universal across subjects and evolves with fatigue and aging.
Why the study?
The study was conducted to understand the coordinated function of distinct fibers in a muscle during maximal exercise across a range of frequency bands and time scales.
Observational
Muscle activation exhibits a universal, muscle-specific spectral profile that evolves with fatigue and aging, suggesting a multiscale mechanism of muscle tone regulation.
Muscle-specific spectral profiles may enable fatigue monitoring; leaves open clinical translation and therapeutic targeting in aging.
To understand coordinated function of distinct fibers in a muscle, we investigated spectral dynamics of muscle activation during maximal exercise across a range of frequency bands and time scales of observation. We discovered a spectral profile that is specific for each muscle type, robust at short, intermediate, and large time scales, universal across subjects, and characterized by a muscle-specific evolution path with accumulation of fatigue and aging, indicating a previously unrecognized multiscale mechanism of muscle tone regulation.
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García‐Retortillo et al. (2020) conducted an observational in Muscle activation. Maximal exercise was evaluated on Spectral dynamics of muscle activation. Maximal exercise revealed a muscle-specific spectral profile of muscle activation that is universal across subjects and evolves with fatigue and aging.
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