Why the study?
Despite evidence showing antimicrobials prevent surgical site infections, inappropriate timing, antibiotic selection, and excessive continuation remain common in practice.
Does evidence-based guideline implementation improve the appropriateness of antibiotic prophylaxis in patients undergoing gastrointestinal surgery?
Does evidence-based guideline implementation improve the appropriateness of antibiotic prophylaxis in patients undergoing gastrointestinal surgery?
Implementation of local evidence-based guidelines can significantly reduce errors in antibiotic use, dose, and duration for gastrointestinal surgeries.
Answers are grounded in this paper and cite their sources.
Guideline implementation improves antibiotic prophylaxis appropriateness in GI surgery; reinforces consensus on perioperative antimicrobial stewardship.
Surgical site infections are related to a high morbidity, mortality and healthcare costs. Despite ample evidence demonstrating the effectiveness of antimicrobials to prevent surgical site infections, inappropriate timing, antibiotic selection and excessive continuation of antibiotics are common in practice. In this study, we compare the appropriateness of antibiotic prophylaxis in gastrointestinal surgery, before and after an evidence-based guideline implementation. One hundred patients were evaluated in each group. The implementation of the guideline resulted in significant reduction of incorrect use of antibiotics from 55% to 18% (P = 0.002). It also reduced duration of prophylactic antibiotics (43% vs. 23%, P = 0.025). Inappropriate doses diminished but not significantly (8% vs. 5%, P = 0.321). Based on our results, in more than half of of these cases patients received incorrect antibiotic prophylaxis regimens for gastrointestinal surgery in this hospital. Local guideline implementation can result in reduction of antibiotic use, dose and duration errors.
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Elyasi et al. (2019) studied Gastrointestinal surgery (n=200). Evidence-based guideline implementation for antibiotic prophylaxis vs. Before guideline implementation was evaluated on Incorrect use of antibiotics (p=0.002). Implementation of an evidence-based guideline for antibiotic prophylaxis in gastrointestinal surgery significantly reduced the incorrect use of antibiotics from 55% to 18% (P=0.002).
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